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Molecular Pathology
for
Precision Medicine

Exciting News: Offspring Biosciences and Flagship Biosciences in new partnership

Home: About

We are a research focused contract services organisation that promotes scientific excellence in the discovery of treatments for human diseases

Supporting Your Project | Research services for informative and reliable high quality data

Supporting Your Project

Research services for informative and reliable high quality data

Validating Your Target | Assay development and expression studies in normal and disease- affected tissues from humans and animal models

Validating Your Target

Assay development and expression studies in normal and disease- affected tissues from humans and animal models

Analysing Drug Efficacy | Discovery of efficacy biomarkers and quantitative analysis of biomarkers in tissues from preclinical drug treatment studies

Analysing Drug Efficacy

Discovery of efficacy biomarkers and quantitative analysis of biomarkers in tissues from preclinical drug treatment studies

Profiling Drug Binding Properties | Literature review, design, proof of concept, execution, analyses including full study report

Profiling Drug Binding Properties

Literature review, design, proof of concept, execution, analyses including full study report

Characterizing Tissue Pathology | Aquisition, QC assessment and pathological characterization of tissues. Multiplexed profiling using anatomic, phenotypic and functional biomarkers. Reviewed by board-certified pathologists

Characterizing Tissue
Pathology

Aquisition, QC assessment and pathological characterization of tissues.  Multiplexed profiling using anatomic, phenotypic and functional biomarkers.  Reviewed by board-certified pathologists

Enhancing Your Research | Research services aligned to your human disease studies

Enhancing Your Research

Research services aligned to your human disease studies

Neurological Disorders | Alzheimer's Disease Parkinson's Disease Multiple Sclerosis Chronic Pain Stroke

Neurological Disorders

​

Alzheimer's Disease

Parkinson's Disease

Multiple Sclerosis

Chronic Pain

Stroke

Oncology & Immuno-Oncology | Pancreatic Cancer Colorectal Cancer Breast Cancer Lung Cancer Melanoma

Oncology & Immuno-Oncology

 

Pancreatic Cancer

Colorectal Cancer

Breast Cancer

Lung Cancer

Melanoma

Metabolic Diseases | Polycystic Kidney Disease Dyslipidemia Diabetes NAFLD NASH

Metabolic Diseases


Diabetes

NAFLD

NASH

Respiratory Diseases | Allergic Rhinitis Lung Fibrosis Asthma COPD BPD

Respiratory Diseases


Lung Fibrosis
Asthma

COPD

BPD

Featured Analyses & Expertise | Molecular pathology services for drug discovery research

Featured Analyses & Expertise

Molecular pathology services for drug discovery research

Multiplexed Tissue Analysis | Pre-established and custom panels RNAscope dual and triplex ISH Nanostring gene expression

Multiplexed
Tissue
Analysis

Pre-established and custom panels

RNAscope dual and triplex ISH

Nanostring gene expression

AI-Powered Quantitative Image Analysis | Phenotypic characterization Spatial distribution Cell interactions

AI-Powered
Quantitative
Image Analysis

Phenotypic characterization

Spatial distribution

Cell interactions

Biomarker Discovery Program | Develop and validate customized assays Transfer assays developed in-house High quality clinical biosamples

Develop and validate customized assays

Transfer assays developed in-house

High quality clinical biosamples

​

Biomarker
Discovery
Program

Validated Target Engagement | Profiling drug binding properties Receptor autoradiography PET imaging

Validated
Target
Engagement

Profiling drug binding properties

Receptor autoradiography

PET imaging

New Featured Assays for
Multiplexed Tissue Analysis

Preclinical biomarker panels now available

CYTOTOXIC T-CELL & NATURAL KILLER CELL ACTIVITY

CD8 - green
NCR1 - purple
Granzyme B - red
Ki-67 - yellow
Nuclear - blue

CYTOTOXIC T-CELL & NATURAL KILLER CELL ACTIVITY | CD8 NCR1 Granzyme B Ki-67 Nuclear

TUMOUR PHENOTYPE
& ACTIVITY

Epithelial - green
Vimentin - red
Ki-67 - yellow 
QC marker - purple
Nuclear - blue

TUMOUR PHENOTYPE & ACTIVITY | Epithelial Vimentin Ki-67 QC marker Nuclear

HELPER T-CELL
ACTIVITY

CD4 - purple
FOXP3 - orange
PD-1 - green
TIM3 - red
Nuclear - blue

HELPER T-CELL ACTIVITY | CD4 FOXP3 PD-1 TIM3 Nuclear

- Thanks for scrolling all the way down! Please Contact Us if you are even more curious.

/Offspring Biosciences - Molecular Pathology For Precision Medicine

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