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Insights & Updates


Surviving the Phase II Cliff: Why So Many Promising Drugs Fail — and What We Can Do About It
For translational leaders, generating decision-quality data before risking millions in clinical trials is crucial. De-Risk Antibody Development with Tissue Insights Platform.
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Surviving the Phase II Cliff: Why So Many Promising Drugs Fail — and What We Can Do About It
For translational leaders, generating decision-quality data before risking millions in clinical trials is crucial. De-Risk Antibody Development with Tissue Insights Platform.
evadanielson55
Mar 122 min read


De-Risking Synucleinopathy Therapeutics: A Human Tissue-First Framework for Target Validation
The transition from preclinical promise to clinical efficacy, the so-called "Translational Gap", remains the most perilous stage of drug development. Nowhere is this chasm wider than in neurodegeneration, where billions of dollars and years of research are lost when promising candidates fail in late-stage trials. The fundamental reason is often a stark divergence between the simplified environments of preclinical models and the complex, heterogeneous reality of human disease.
evadanielson55
Feb 24 min read


Validating CNS Therapeutics
Human Tissue Analysis in CNS drug development helps to bridge the translational gap and de-risk clinical development. New research on Alzheimers Disease, Palsy, Parkinsons, Multi System Atrophy and more offer insights into treatment development.
evadanielson55
Jan 274 min read
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