top of page

Insights & Updates


Surviving the Phase II Cliff: Why So Many Promising Drugs Fail — and What We Can Do About It
For translational leaders, generating decision-quality data before risking millions in clinical trials is crucial. De-Risk Antibody Development with Tissue Insights Platform.
Featured
Search


Offspring Biosciences in research collaboration with BioArctic
We are proud to have the opportunity to work in collaboration together with BioArctic in this study we have been performing IHC binding of Lecanemab in Down syndrome and Alzheimer's disease This study shows for or the first time, Lecanemab (an antibody with higher avidity for toxic Aβ aggregates), binding to Aβ protofibrils and plaques in people with Down syndrome is demonstrated Lecanemab currently in phase 3 clinical studies and has shown to reduce brain amyloid levels in t
-
Sep 16, 20211 min read


Offspring Biosciences in research collaboration developing alpha-synuclein PET ligand
New publication, “Identification and in vitro characterization of C05-01, a PBB3 derivative with improved affinity for alpha-synuclein” together with Karolinska Institutet, Andrea Varrone research group. The approach used in this study also shows that TMAs are a useful tool for the evaluation of ligands in tissue from different proteinopathies, using both fluorescence and autoradiographic assays https://doi.org/10.1016/j.brainres.2020.147131 The neuropathological hallmark o
-
Sep 16, 20211 min read


Developing a new drug is a long and costly process with many pitfalls
Most projects are closed down before the drug has reached the market. With the support of Offspring Bioscience's unique expertise in tissue analysis, pharmaceutical companies significantly improve the odds of success "Our unique ability to plan and carry out such analyses is based on the experience we have built up over a long period of time through our work on pharmaceutical projects in the pharmaceutical industry. With efficient methods and refined analytical techniques,
-
Sep 16, 20211 min read
bottom of page
