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Insights & Updates


Four Reasons Antibody Programs Fail Before They Reach Patients
The most successful translational strategies increasingly focus on generating human-relevant evidence earlier, when development teams still have the opportunity to refine candidate selection, optimize trial design, and reduce uncertainty before major investments are made.
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Every Failed Program Looked Promising Once
Drug discovery has always involved making high-stakes decisions before all the answers are available. The challenge for R&D leadership is determining which uncertainties are acceptable, and which are systemic liabilities capable of derailing an entire program at the clinical threshold.
evadanielson55
Jun 154 min read


Decoding the Brain: The Evolving Challenge of Neurological Drug Development
Neurology is one of the most complex and challenging frontiers in medicine, encompassing a vast spectrum of disorders that affect the central and peripheral nervous system, behavioral and mood changes, and extending changes in hormones and the microbiome. This includes progressive neurodegenerative conditions like Alzheimer’s Disease and Parkinson’s Disease, defined by the toxic aggregation of proteins like Amyloid-beta and alpha-synuclein; autoimmune disorders like Multiple
evadanielson55
Mar 173 min read


Validating CNS Therapeutics
Human Tissue Analysis in CNS drug development helps to bridge the translational gap and de-risk clinical development. New research on Alzheimers Disease, Palsy, Parkinsons, Multi System Atrophy and more offer insights into treatment development.
evadanielson55
Jan 274 min read
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