Biosciences
Offspring
Multiplex Tissue Analysis
Analyzing multiple biomarkers in tissues with preserved anatomical context presents compelling opportunities to uncover crucial insights into the underlying mechanisms driving diverse disease processes. This approach is increasingly gaining traction in clinical research and among pharmaceutical teams, serving as invaluable tools for target validation, efficacy analyses, and patient stratification.
However, executing such analyses is a complex undertaking, demanding significant investments in expensive infrastructure, finely calibrated and integrated workflows, and highly trained staff. This challenge becomes even more pronounced when handling larger cohorts of tissues that require meticulous processing and quantitative analysis.
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At Offspring, we offer a unique capability and capacity to efficiently co-process large quantities of tissues for the analysis of multiple biomarkers. Leveraging multiplexed immunofluorescence or immunohistochemical , as well as Nanostring-based analyses, along with pre-established or custom-built biomarker panels, we combine these capabilities with agile digital scanning of stained tissue sections. Our approach incorporates deep learning AI-powered quantitative image analysis, ensuring the generation of reliable data crucial for making informed stop/go decisions. This comprehensive solution is designed to meet the rigorous demands of spatial biology research, providing a streamlined and effective means to extract valuable insights from tissue analyses."
Offspring Biosciences is set up to assist your projects with co-staining of multiple biomarkers in tissue sections using a range of techniques, including up to 6-plexed immunohistofluorescence (IHF), 3-plexed chromogenic immunohistochemistry (IHC) and 2-plexed in situ hybridization histochemistry (ISH). We perform these analyses with pre-established panels for multiplexed biomarker staining or by custom build to flexibly adapt their design to your specific needs.
